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HCPCS J2720 (Protamine Sulfate) Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, protamine sulfate, per 10 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

22 - On Campus Outpatient Hospital

Complexity LevelLow
Medicare Payment Limit
$1.745BuyandBill.com
WAC Price
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Related NDC Codes

63323-0229-05 - PROTAMINE SULFATE (S.D.V.) 10 MG/ML

63323-0229-15 - NOVAPLUS PROTAMINE SULFATE (25X5ML,SDV,FLIPTOP,USP) 10 MG/ML

63323-0229-30 - PROTAMINE SULFATE (S.D.V.) 10 MG/ML

63323-0229-35 - NOVAPLUS PROTAMINE SULFATE (1X25ML,SDV,FLIPTOP,USP) 10 MG/ML


National average reimbursement for HCPCS J2720 by major payers:

bcbs

$1.22

uhc

$1.19

aetna

$1.27

cigna

$1.20

Preview provider-level rates for...
For billing codeHCPCS J2720
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J2720

United
J2720$1.131912954553 - MERCY HEALTH, MERCY HEALTH - ST ANNE HOSPITAL264779623OHGeneral Acute Care Hospital (282N00000X)
United
J2720$2.131669565180 - MARYLAND GENERAL HOSPITAL INC, UNIVERSITY OF MARYLAND MEDICAL CENTER MIDTOWN CAMPUS520591667 - (MD) MARYLAND GENERAL HOSPITALMDGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081306886866 - CRAIG COUNTY HOSPITAL AUTHORITY, CRAIG GENERAL HOSPITAL731430157 - (OK) CRAIG COUNTY HOSPITAL AUTHORITYOKGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081982604021 - GEORGETOWN MEMORIAL HOSPITAL, TIDELANDS GEORGETOWN MEMORIAL HOSPITAL570341194 - GEORGETOWN MEMORIAL HOSPITALSCGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081801846126 - TUSCALOOSA VAMC630297932 - (AL) TUSCALOOSA VAMCALGeneral Acute Care Hospital (282N00000X)
United
J2720$1.131073834529 - MOUNTAIN VIEW HOSPITAL PHYSICIAN ORGANIZATION820516012 - MOUNTAIN VIEW HOSPITAL LLCIDGeneral Acute Care Hospital (282N00000X)
United
J2720$1.131558315010 - SOUTHWEST HEALTHCARE OF BROWN COUNTY OHIO, LLC, SOUTHWEST REGIONAL MEDICAL CENTER316001668OHGeneral Acute Care Hospital (282N00000X)
United
J2720$1.451235174327 - GRADY MEMORIAL HOSPITAL314379436 - (OH) OHIOHEALTH CORPORATIONOHGeneral Acute Care Hospital (282N00000X)
United
J2720$3.131437396348 - ELK REGIONAL HEALTH CENTER, PENN HIGHLANDS ELK250585280 - (PA) ELK REGIONAL HEALTH CENTERPAGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081568459436 - POCONO MEDICAL CENTER, LEHIGH VALLEY HOSPITAL POCONO240795623 - (PA) POCONO MEDICAL CENTERPAGeneral Acute Care Hospital (282N00000X)
United
J2720$2.191851927669 - NORTHWEST SAHUARITA HOSPITAL LLC, NORTHWEST MEDICAL CENTER SAHUARITA384088744 - (AZ) NORTHWEST SAHUARITA HOSPITAL LLCAZGeneral Acute Care Hospital (282N00000X)
United
J2720$5.131336244474 - UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, UCSF MEDICAL CENTER943281660CAGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081447571658 - SUMNER REGIONAL MEDICAL CENTER LLC, SUMNER REGIONAL MEDICAL CENTER621573738 - (TN) SUMNER REGIONAL HEALTH SYSTEM, INC.TNGeneral Acute Care Hospital (282N00000X)
United
J2720$1.131497784144 - MERCER COUNTY JOINT TOWNSHIP COMMUNITY HOSPITAL, MERCER HEALTH341101385OHGeneral Acute Care Hospital (282N00000X)
United
J2720$1.081730115940 - HILLSDALE COMMUNITY HEALTH CENTER, HILLSDALE HOSPITAL386005550 - HILLSDALE COMMUNITY HEALTH CENTERMIGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J2720 vs. Other Drugs, Administered by Injection Codes

The HCPCS J2720 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J2720 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
63323-0229-05-NDCModeratePROTAMINE SULFATE (S.D.V.) 10 MG/ML
J2710-HCPCSLowInjection, neostigmine methylsulfate, up to 0.5 mg
J2720-HCPCSLowInjection, protamine sulfate, per 10 mg
J2724-HCPCSLowInjection, protein C concentrate, intravenous, human, 10 IU

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J2720. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J2720 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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