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HCPCS J2998 (Ryplazim) Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, plasminogen, human-tvmh, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

99 - Other POS

Complexity LevelLow
WAC Price
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National average reimbursement for HCPCS J2998 by major payers:

bcbs

$33.99

uhc

$34.70

aetna

$34.17

cigna

$35.04

Preview provider-level rates for...
For billing codeHCPCS J2998
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J2998

United
J2998$34.341235417288 - SOUTHEASTERN REGIONAL MEDICAL CENTER, INC., SOUTHEASTERN REGIONAL MEDICAL CENTER, LLC264572436 - (GA) SOUTHEASTERN REGIONAL MEDICAL CENTER LLCGAGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971588668842 - HALIFAX REGIONAL HOSPITAL, INC., SENTARA HALIFAX REGIONAL HOSPITAL540648699 - (VA) HALIFAX REGIONAL HOSPITAL INCVAGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971235666033 - CONWAY REGIONAL HEALTH SYSTEM710249735 - CONWAY REGIONAL MEDICAL CENTER INCARGeneral Acute Care Hospital (282N00000X)
United
J2998$40.491396923710 - EMORY UNIVERSITY HOSPITAL582030692 - EMORY UNIVERSITYGAGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971225272552 - MAPLE GROVE HOSPITAL CORPORATION411843943 - UNIVERSITY OF MINNESOTA PHYSICIANSMNGeneral Acute Care Hospital (282N00000X)
United
J2998$40.431629006457 - REGIONS HOSPITAL410797853 - GROUP HEALTH PLAN INCMNGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971730684853 - PRESBYTERIAN HEALTHCARE SERVICES, PRESBYTERIAN SANTA FE MEDICAL CENTER850105601 - PRESBYTERIAN HEALTHCARE SERVICESNMGeneral Acute Care Hospital (282N00000X)
United
J2998$33.581023006434 - BAYHEALTH MEDICAL CENTER, INC., BAYHEALTH HOSPITAL, SUSSEX CAMPUS510064318 - BAYHEALTH MEDICAL CENTER INCDEGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971093768962 - MERCY HEALTH SYSTEM CORPORATION, MERCY HOSPITAL JANESVILLE390816848 - MERCY HEALTH SYSTEM CORPORATIONWIGeneral Acute Care Hospital (282N00000X)
United
J2998$48.001841271459 - WEST VIRGINIA UNIVERSITY HOSPITALS, INC, WVU HOSPITALS, INC550643304 - WEST VIRGINIA UNIVERSITY HOSPITALS INCWVGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971174573547 - MONTGOMERY VAMC630288981ALGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971255380242 - LEXINGTON VAMC, LEXINGTON COOPER VAMC610443527 - (KY) LEXINGTON VAMCKYGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971679663835 - CAROLE DUBUCHE132828349 - SUN RIVER HEALTH INCNYGeneral Acute Care Hospital (282N00000X)
United
J2998$40.771598895690 - ASANTE THREE RIVERS MEDICAL CENTER LLC, TRMC PROFESSIONAL SERVICES571181758 - (OR) ASANTE THREE RIVERS MEDICAL CENTER LLCORGeneral Acute Care Hospital (282N00000X)
United
J2998$33.971497275853 - ALEXANDER TRAN MD PA821967465 - (TX) ALEXANDER TRAN MD PATXGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J2998 vs. Other Drugs, Administered by Injection Codes

The HCPCS J2998 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J2998 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
J2997-HCPCSLowInjection, alteplase recombinant, 1 mg
J2998-HCPCSLowInjection, plasminogen, human-tvmh, 1 mg
J3000-HCPCSLowInjection, streptomycin, up to 1 gm

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J2998. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J2998 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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