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HCPCS S0021 Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, cefoperazone sodium, 1 gram
Key FactDetail
Service Type

Temporary National Codes (Non-Medicare)

Non-Medicare Drug Codes

Common Place of Service

None

11 - Office

20 - Urgent Care Facility

Complexity LevelLow

National average reimbursement for HCPCS S0021 by major payers:

bcbs

$33.03

uhc

$18.26

aetna

$16.05

cigna

$15.43

Preview provider-level rates for...
For billing codeHCPCS S0021
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS S0021

United
S0021$18.001225257801 - LEIF MEYERS454551946 - (ID) TETON VALLEY HEALTH CARE INCMIEmergency Medicine Physician (207P00000X)
United
S0021$18.211598793036 - DANIEL ZIMMERMAN861441258NCPhysician Assistant (363A00000X)
United
S0021$18.001942629126 - AMBER VESTER931251530ORFamily Medicine Physician (207Q00000X)
United
S0021$18.001285658625 - ANN BOWERS911579410 - (WA) PHYSICIANS IMMEDIATE CARE MEDICAL CENTERS PSOREmergency Medicine Physician (207P00000X)
United
S0021$18.001245391192 - JONELL BLASE930593500 - (OR) DOCTORS EMERGENCY ROOM CORP PCORFamily Nurse Practitioner (363LF0000X)
United
S0021$18.001205022688 - JEANNE CULLEN201508867ORRegistered Dietitian (133V00000X)
United
S0021$18.001720590987 - PAMELA COTTON930593500 - (OR) DOCTORS EMERGENCY ROOM CORP PCORFamily Nurse Practitioner (363LF0000X)
United
S0021$18.001386909851 - KYLE KURZET930421470 - (OR) WILLAMETTE COMMUNITY HEALTH SOLUTIONSORFamily Medicine Physician (207Q00000X)
United
S0021$18.001285658625 - ANN BOWERS911579410 - (WA) PHYSICIANS IMMEDIATE CARE MEDICAL CENTERS PSOREmergency Medicine Physician (207P00000X)
United
S0021$18.001598793036 - DANIEL ZIMMERMAN930593500 - (OR) DOCTORS EMERGENCY ROOM CORP PCOKPhysician Assistant (363A00000X)
United
S0021$18.001598359234 - ZACHERY EHRENFELT930421470 - (OR) WILLAMETTE COMMUNITY HEALTH SOLUTIONSORPhysical Therapist (225100000X)
United
S0021$18.001124242086 - KATHY MELDRUM930421470 - (OR) WILLAMETTE COMMUNITY HEALTH SOLUTIONSORPhysical Therapist (225100000X)
United
S0021$18.001376327809 - JULIA O'NEIL930421470 - (OR) WILLAMETTE COMMUNITY HEALTH SOLUTIONSORRegistered Dietitian (133V00000X)
United
S0021$18.001750693552 - JUDITH EMMANERE930421470 - (OR) WILLAMETTE COMMUNITY HEALTH SOLUTIONSORHand Occupational Therapist (225XH1200X)
United
S0021$18.001093741803 - CHARLES PEDERSON930593500 - (OR) DOCTORS EMERGENCY ROOM CORP PCOROccupational Medicine Physician (2083X0100X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS S0021 vs. Other Non-Medicare Drug Codes Codes

The HCPCS S0021 code is part of the Temporary National Codes (Non-Medicare) services used for Non-Medicare Drug Codes. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS S0021 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
S0017-HCPCSLowInjection, aminocaproic acid, 5 grams
S0021-HCPCSLowInjection, cefoperazone sodium, 1 gram
S0023-HCPCSLowInjection, cimetidine hydrochloride, 300 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS S0021. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the S0021 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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