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See a sample rate comparisonHCPCS S0021 Fee Schedule
Last Verified: September 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Injection, cefoperazone sodium, 1 gram
| Key Fact | Detail |
|---|---|
| Service Type | Temporary National Codes (Non-Medicare) Non-Medicare Drug Codes |
| Common Place of Service | None 11 - Office 20 - Urgent Care Facility |
| Complexity Level | Low |
| Medicaid Fee Schedule | View Medicaid rates for S0021 |
National average reimbursement for HCPCS S0021 by major payers:
$33.03
$18.26
$16.05
$15.43
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HCPCS S0021
5 of 25 sample ratesHigher to lower in this preview
Daniel Zimmerman
$18.21Published rateShanlee Pierson
Willamette Community Health Solutions
$18.00Published rateWillamette Community Health Solutions, Cascade Health Solutions
Willamette Community Health Solutions
$18.00Published rateAndrea Leiserowitz
Willamette Community Health Solutions
$18.00Published rateAmber Vester
$18.00Published rate
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See a sample payer proposalHCPCS S0021 vs. Other Non-Medicare Drug Codes Codes
The HCPCS S0021 code is part of the Temporary National Codes (Non-Medicare) services used for Non-Medicare Drug Codes. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The HCPCS S0021 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| S0021-HCPCS | Low | Injection, cefoperazone sodium, 1 gram |
| S0023-HCPCS | Low | Injection, cimetidine hydrochloride, 300 mg |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS S0021. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the S0021 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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