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CPT 80334 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Definitive Drug Testing; Antidepressants, Serotonergic Class; 6 Or More
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

XU - Unusual Non-Overlapping Service

Complexity LevelLow

National average reimbursement for CPT 80334 by major payers:

bcbs

$20.20

uhc

$24.64

aetna

$1.27

cigna

$62.99

Preview provider-level rates for...
For billing codeCPT 80334
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 80334

United
80334$8.751265437644 - WEST JEFFERSON HOLDINGS, LLC, WEST JEFFERSON MEDICAL CENTER472667968 - WEST JEFFERSON HOLDINGS, LLCLAGeneral Acute Care Hospital (282N00000X)
United
80334$8.751396394961 - CLHG-ACADIAN, LLC, ACADIAN MEDICAL CENTER825359949LAGeneral Acute Care Hospital (282N00000X)
United
80334$5.821467442418 - NORTHWEST TEXAS HEALTHCARE SYSTEM INC, NORTHWEST TEXAS HEALTHCARE SYSTEM232238976TXGeneral Acute Care Hospital (282N00000X)
United
80334$9.541073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80334$8.751497792527 - UNIVERSITY HEALTHCARE SYSTEM, L.C., TULANE LAKESIDE HOSPITAL621596506LAGeneral Acute Care Hospital (282N00000X)
United
80334$8.751396394961 - CLHG-ACADIAN, LLC, ACADIAN MEDICAL CENTER825359949LAGeneral Acute Care Hospital (282N00000X)
United
80334$8.751689676835 - NATCHITOCHES PARISH HOSPITAL SERVICE DISTRICT, NATCHITOCHES REGIONAL MEDICAL CENTER726013916 - (LA) NATCHITOCHES REGIONAL MEDICAL CENTERLAGeneral Acute Care Hospital (282N00000X)
United
80334$8.751528027240 - FAYETTE COMMUNITY HOSPITAL, INC., PIEDMONT FAYETTE HOSPITAL582322328 - (GA) FAYETTE COMMUNITY HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
80334$5.821972071991 - GAINESVILLE COMMUNITY HOSPITAL, INC., NORTH TEXAS MEDICAL CENTER831683025 - (TX) GAINESVILLE COMMUNITY HOSPITAL INCTXGeneral Acute Care Hospital (282N00000X)
United
80334$8.751982600540 - UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER, INC., PIEDMONT MCDUFFIE HOSPITAL454166209 - (GA) UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80334$8.751255401519 - THE MEDICAL CENTER INC, PIEDMONT COLUMBUS REGIONAL MIDTOWN581685139 - (GA) THE MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80334$9.541073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80334$9.541073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80334$8.751407947336 - CLHG-VILLE PLATTE LLC, MERCY REGIONAL MEDICAL CENTER824681222LAGeneral Acute Care Hospital (282N00000X)
United
80334$5.821881665164 - CLHG-LEESVILLE, BYRD REGIONAL HOSPITAL824337635LAGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 80334 vs. Other Therapeutic Drug Assays Codes

The CPT 80334 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80334 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80331-CPTLowDefinitive Drug Testing; Analgesics, Non-Opioid; 6 Or More
80332-CPTLowDefinitive Drug Testing; Antidepressants, Serotonergic Class; 1 Or 2
80333-CPTLowDefinitive Drug Testing; Antidepressants, Serotonergic Class; 3-5
80334-CPTLowDefinitive Drug Testing; Antidepressants, Serotonergic Class; 6 Or More

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80334. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80334 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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