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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Therapeutic Drug Assays |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory 91 - Repeat Lab Test |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 80345 |
| Medicaid Fee Schedule | $14.90 median of the 6 states in the free preview · View Medicaid rates for 80345 |
National average reimbursement for CPT 80345 by major payers:

$19.65

$13.00

$2.41

$45.76
Choose a payer to see a sample of rates for CPT 80345.
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
Baycare Home Care, Inc.
Baycare Home Care Inc
Progressive Emergency Physicians PLLC
Willamette Community Health Solutions, Cascade Health Solutions
Sunrise Home Health Care Inc.
Sunrise Home Health Care Inc
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Rate Benchmarking
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See a sample rate comparisonPayer Contract Negotiation
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See a sample payer proposalCPT 80345 vs. Other Therapeutic Drug Assays Codes
The CPT 80345 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 80345 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 80345-CPT | Low | Barbiturate Drug Screening, This Test Measures The Amount Of Barbiturates Present In Blood And Urine Samples. Barbiturates Work On The Central Nervous System And Have Been Used As Sleeping Pills. |
| 80348-CPT | Low | Buprenorphine Drug Screening, This Test Measures The Amount Of Buprenorphine Present In Blood And Urine Samples. |
| 80353-CPT | Low | Cocaine Drug Screening, The Test Measures The Amount Of Cocaine In A Blood Or Urine Sample. |
| 80354-CPT | Low | Fentanyl Drug Screening, This Test Measures The Amount Of Fentanyl Present In Blood And Urine Samples. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80345. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 80345 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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