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See a sample rate comparisonCPT 80353 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Cocaine Drug Screening, The Test Measures The Amount Of Cocaine In A Blood Or Urine Sample.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Therapeutic Drug Assays |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 80353 |
| Medicaid Fee Schedule | $12.97 median of the 6 states in the free preview · View Medicaid rates for 80353 |
National average reimbursement for CPT 80353 by major payers:
$21.00
$14.17
$1.93
$50.92
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CPT 80353
5 of 25 sample ratesHigher to lower in this preview
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
$63.36Published rateAsya Segalene
Allergy & Asthma Of Dupage, S.C.
$21.81Published rateChu Chen
Merrimack Valley Pediatric Associates, Inc.
$12.20Published rateJeremy Kelley
Bama Heart Doc, PC Dba Alabama Heart & Vascular Medicine
$10.15Published rateLeon Home Health, LLC, Leon At Home
$8.60Published rate
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See a sample payer proposalCPT 80353 vs. Other Therapeutic Drug Assays Codes
The CPT 80353 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 80353 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 80345-CPT | Low | Barbiturate Drug Screening, This Test Measures The Amount Of Barbiturates Present In Blood And Urine Samples. Barbiturates Work On The Central Nervous System And Have Been Used As Sleeping Pills. |
| 80348-CPT | Low | Buprenorphine Drug Screening, This Test Measures The Amount Of Buprenorphine Present In Blood And Urine Samples. |
| 80353-CPT | Low | Cocaine Drug Screening, The Test Measures The Amount Of Cocaine In A Blood Or Urine Sample. |
| 80354-CPT | Low | Fentanyl Drug Screening, This Test Measures The Amount Of Fentanyl Present In Blood And Urine Samples. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80353. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 80353 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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