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CPT 80356 Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Definitive Drug Testing; Heroin Metabolite
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 80356

National average reimbursement for CPT 80356 by major payers:

bcbs

$24.25

uhc

$15.59

aetna

$2.23

cigna

$68.69

Preview provider-level rates for...
For billing codeCPT 80356
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 80356

United
80356$17.451013915149 - BAYCARE HOME CARE, INC., DBA SARASOTA MEMORIAL HOME CARE593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80356$60.481073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80356$10.131740453000 - GRAHAM REGIONAL MEDICAL CENTER, GRAHAM GENERAL HSOPITAL PHYSICIANS463113489TXGeneral Acute Care Hospital (282N00000X)
United
80356$17.451821097627 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80356$17.451821081720 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80356$10.361174526529 - TITUS COUNTY HOSPITAL DISTRICT, TITUS REGIONAL MEDICAL CENTER756003935TXGeneral Acute Care Hospital (282N00000X)
United
80356$20.101255766531 - MARISSA LIVERIS362925195 - ALLERGY & ASTHMA OF DUPAGE, S.C.ILPhysician Assistant (363A00000X)
United
80356$10.151679845531 - DANA HEMSTREET451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALFamily Nurse Practitioner (363LF0000X)
United
80356$8.521598375651 - E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLC, E AND A HEALTHCARE ON THE GO832289173 - (FL) E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLCFLHome Health Agency (251E00000X)
United
80356$11.841780694620 - CARSON MEDICAL GROUP PROFESSIONAL CORPORATION880133501 - CARSON MEDICAL GROUPNVObstetrics & Gynecology Physician (207V00000X)
United
80356$15.901073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80356$11.841780694620 - CARSON MEDICAL GROUP PROFESSIONAL CORPORATION880133501 - CARSON MEDICAL GROUPNVObstetrics & Gynecology Physician (207V00000X)
United
80356$63.361073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80356$29.861255478004 - CHRISTOPHER RAIO111888924 - GOOD SAMARITAN HOSPTIAL MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
80356$9.931023438009 - MOLLY MCINTOSH593140335 - BAYCARE MEDICAL GROUP INCFLHome Health Agency (251E00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 80356 vs. Other Therapeutic Drug Assays Codes

The CPT 80356 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80356 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80343-CPTLowDefinitive Drug Testing; Antipsychotics, Not Otherwise Specified; 4-6
80346-CPTLowDefinitive Drug Testing; Benzodiazepines; 1-12
80347-CPTLowDefinitive Drug Testing; Benzodiazepines; 13 Or More
80356-CPTLowDefinitive Drug Testing; Heroin Metabolite

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80356. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80356 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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