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CPT 80364 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Definitive Drug Testing; Opioids And Opiate Analogs; 5 Or More
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

TC - Technical component

Complexity LevelLow

National average reimbursement for CPT 80364 by major payers:

bcbs

$44.18

uhc

$32.15

aetna

$3.96

cigna

$68.28

Preview provider-level rates for...
For billing codeCPT 80364
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 80364

United
80364$14.261689676835 - NATCHITOCHES PARISH HOSPITAL SERVICE DISTRICT, NATCHITOCHES REGIONAL MEDICAL CENTER726013916 - (LA) NATCHITOCHES REGIONAL MEDICAL CENTERLAGeneral Acute Care Hospital (282N00000X)
United
80364$14.261760498588 - PIEDMONT NEWTON HOSPITAL, INC., NEWTON MEDICAL CENTER582155150 - (GA) PIEDMONT NEWTON HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$15.931073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80364$15.931073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80364$14.261811940976 - MACON NORTHSIDE HOSPITAL, LLC, PIEDMONT MACON NORTH HOSPITAL621736985 - (GA) MACON NORTHSIDE HOSPITAL LLCGAGeneral Acute Care Hospital (282N00000X)
United
80364$14.261982600540 - UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER, INC., PIEDMONT MCDUFFIE HOSPITAL454166209 - (GA) UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$14.261225034333 - PIEDMONT HENRY HOSPITAL, INC.582200195 - (GA) PIEDMONT HENRY HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$15.931073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80364$15.931073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80364$14.261982600540 - UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER, INC., PIEDMONT MCDUFFIE HOSPITAL454166209 - (GA) UNIVERSITY MCDUFFIE COUNTY REGIONAL MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$14.261811940976 - MACON NORTHSIDE HOSPITAL, LLC, PIEDMONT MACON NORTH HOSPITAL621736985 - (GA) MACON NORTHSIDE HOSPITAL LLCGAGeneral Acute Care Hospital (282N00000X)
United
80364$14.261437135902 - AU MEDICAL CENTER, INC582144788 - (GA) AU MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$15.931073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
80364$14.261437186111 - PIEDMONT ATHENS REGIONAL MEDICAL CENTER, INC.582179986 - (GA) PIEDMONT ATHENS REGIONAL MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
80364$9.501467442418 - NORTHWEST TEXAS HEALTHCARE SYSTEM INC, NORTHWEST TEXAS HEALTHCARE SYSTEM232238976TXGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 80364 vs. Other Therapeutic Drug Assays Codes

The CPT 80364 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80364 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80346-CPTLowDefinitive Drug Testing; Benzodiazepines; 1-12
80359-CPTLowDefinitive Drug Testing; Methylenedoxyamphetamines (Mda, Mdea, Mdma)
80361-CPTLowDefinitive Drug Testing; Opiates, 1 Or More
80364-CPTLowDefinitive Drug Testing; Opioids And Opiate Analogs; 5 Or More

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80364. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80364 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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