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CPT 81166 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Brca1 Gene Full Dup Del Alys, Brca1 Brca1 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

Common Modifiers

None

90 - Reference Laboratory

GW - Condition not related to the patient's terminal condition

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81166
Medicaid Fee ScheduleView Medicaid rates for 81166

National average reimbursement for CPT 81166 by major payers:

bcbs

$237.26

uhc

$184.72

aetna

$278.74

cigna

$454.38

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81166.

CPT 81166
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $662.97Published rate
  2. Christopher Raio

    Samaritan Emergency Medical Services PC

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 20-8243412

    $397.78Published rate
  3. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1134127301Tax ID 59-3582520

    $222.22Published rate
  4. Ausencio Nunez

    Progressive Medical Center, S.C.

    ILInternal Medicine PhysicianNPI 1407996564Tax ID 36-3950044

    $165.74Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $105.47Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81166 vs. Other Molecular Pathology Procedures Codes

The CPT 81166 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81166 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81162-CPTHighBrca1 2 Gen Full Seq Dup Del, Brca1 Brca1 Dna Repair Associated Brca2 Brca2 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Sequence Analysis And Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements
81164-CPTModerateBrca1 2 Gen Ful Dup Del Alys, Brca1 Brca1 Dna Repair Associated Brca2 Brca2 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements
81165-CPTModerateGenetic Test For Cancer, A Lab Analysis Of Genetic Material That Can Indicate Various Types Of Cancer. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81166-CPTModerateBrca1 Gene Full Dup Del Alys, Brca1 Brca1 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81166. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81166 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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