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CPT 81240 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

F2 (Prothrombin Coagulation Factor Ii) (Eg Hereditary Hypercoagulability) Gene Analysis 20210g>A Variant
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow

National average reimbursement for CPT 81240 by major payers:

bcbs

$51.91

uhc

$40.66

aetna

$64.69

cigna

$126.30

Preview provider-level rates for...
For billing codeCPT 81240
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81240

United
81240$67.431255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81240$65.691841843455 - HCN EP HORIZON CITY, LLC, THE HOSPITALS OF PROVIDENCE EMERGENCY ROOM MONTWOOD813935393 - (TX) HCN EP HORIZON CITY LLCTXGeneral Acute Care Hospital (282N00000X)
United
81240$161.801710979935 - ROBERT DAUL391731465 - (WI) NEUROSCIENCE GROUP OF NORTHEAST WISCONSIN, S.C.WIPhysical Therapist (225100000X)
United
81240$52.551255766531 - MARISSA LIVERIS362925195 - ALLERGY & ASTHMA OF DUPAGE, S.C.ILPhysician Assistant (363A00000X)
United
81240$161.801801401252 - JODI TESCH391731465 - (WI) NEUROSCIENCE GROUP OF NORTHEAST WISCONSIN, S.C.WINurse Practitioner (363L00000X)
United
81240$65.691073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
81240$65.691548232044 - LAREDO TEXAS HOSPITAL COMPANY LP, LAREDO MEDICAL CENTER200175530TXGeneral Acute Care Hospital (282N00000X)
United
81240$27.591487771705 - DONNA MEDICAL CLONIC223875437 - (TX) DONNA MEDICAL CLINIC, P.A.TXGeneral Acute Care Hospital (282N00000X)
United
81240$144.521073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
81240$161.801093820219 - KIMBERLY KARRMANN391731465 - (WI) NEUROSCIENCE GROUP OF NORTHEAST WISCONSIN, S.C.WIPhysical Therapist (225100000X)
United
81240$65.691437102639 - COLUMBIA MEDICAL CENTER OF MCKINNEY SUBSIDIARY LP, MEDICAL CITY MCKINNEY621682207 - (TX) COLUMBIA MEDICAL CENTER OF MCKINNEY SUBSIDIARY LPTXGeneral Acute Care Hospital (282N00000X)
United
81240$161.801902030380 - KRISTEN MUSSER391731465 - (WI) NEUROSCIENCE GROUP OF NORTHEAST WISCONSIN, S.C.WIPhysical Therapist (225100000X)
United
81240$67.431255478004 - CHRISTOPHER RAIO208243412 - SAMARITAN EMERGENCY MEDICAL SERVICES PCNYEmergency Medicine Physician (207P00000X)
United
81240$27.591053866707 - BRITTANY PTACHICK541958039 - HROA 401K PLANVAFamily Nurse Practitioner (363LF0000X)
United
81240$144.521073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81240 vs. Other Molecular Pathology Procedures Codes

The CPT 81240 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81240 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81235-CPTModerateEgfr (Epidermal Growth Factor Receptor) (Eg, Non-Small Cell Lung Cancer) Gene Analysis, Common Variants (Eg, Exon 19 Lrea Deletion, L858r, T790m, G719a, G719s, L861q)
81236-CPTModerateEzh2 (Enhancer Of Zeste 2 Polycomb Repressive Com-Plex Subunit) (Eg Myelodysplastic Syndrome Myeloproliferative Neoplasms) Gene Analysis Full Gene Sequence
81237-CPTLowEzh2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit) (Eg Diffuse Large B-Cell Lymphoma) Gene Analysis Common Variant(S) (Eg Codon 646)
81240-CPTLowF2 (Prothrombin Coagulation Factor Ii) (Eg Hereditary Hypercoagulability) Gene Analysis 20210g>A Variant

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81240. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81240 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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