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CPT 81241 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

F5 (Coagulation Factor V)(Eg Hereditary Hypercoagulability) Gene Analysis Leiden Variant
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

59 - Distinct Procedural Service

Complexity LevelLow

National average reimbursement for CPT 81241 by major payers:

bcbs

$59.20

uhc

$47.69

aetna

$71.48

cigna

$137.45

Preview provider-level rates for...
For billing codeCPT 81241
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81241

United
81241$73.371114998911 - GRANBURY HOSPITAL CORPORATION, LAKE GRANBURY MEDICAL CENTER752682017 - (TX) GRANBURY HOSPITAL CORPORATIONTXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371063466035 - CHCA CLEAR LAKE LP, HCA HOUSTON HEALTHCARE CLEAR LAKE621801360TXGeneral Acute Care Hospital (282N00000X)
United
81241$83.371548588841 - HARLINGEN VAMC272466786TXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371841844735 - EMERUS BHS SA THOUSAND OAKS, LLC, BAPTIST NEIGHBORHOOD HOSPITAL KELLY452497248 - (TX) EMERUS BHS SA THOUSAND OAKS LLCTXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371700801909 - TENET HOSPITALS LIMITED, THE HOSPITALS OF PROVIDENCE MEMORIAL CAMPUS954537720TXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371679528889 - ST. DAVID'S HEALTHCARE PARTNERSHIP, L.P., LLP, ST. DAVID'S SOUTH AUSTIN MEDICAL CENTER742781812TXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371649223645 - ST DAVIDS HEALTHCARE PARTNERSHIP LP LLP, ROUND ROCK MEDICAL CENTER742781812TXGeneral Acute Care Hospital (282N00000X)
United
81241$35.021275581852 - ROLLING PLAINS MEMORIAL HOSPITAL756003896 - (TX) THE NOLAN COUNTY HOSPITAL DISTRICTTXGeneral Acute Care Hospital (282N00000X)
United
81241$75.021902469653 - CLHG-DEQUINCY, LLC364911029 - (LA) CLHGDEQUINCY LLCLACritical Access Hospital (282NC0060X)
United
81241$73.371003344334 - HCN EP HORIZON CITY, LLC, THE HOSPITALS OF PROVIDENCE HORIZON CITY CAMPUS813935393 - (TX) HCN EP HORIZON CITY LLCTXGeneral Acute Care Hospital (282N00000X)
United
81241$35.021144766569 - PARAGON HOSPITALIST, LLC814432519 - (TX) PARAGON HOSPITALIST LLCTXGeneral Acute Care Hospital (282N00000X)
United
81241$50.021609135904 - ANDREW CORONA273026151 - (TX) MID COAST MEDICAL CENTER-CENTRALTXGeneral Acute Care Hospital (282N00000X)
United
81241$35.021457358103 - BELLVILLE HOSPITAL DISTRICT, BELLVILLE GENERAL HOSPITAL274005511 - BELLVILLE MEDICAL CENTERTXGeneral Acute Care Hospital (282N00000X)
United
81241$73.371205307378 - CHEROKEE MEDICAL CENTER, CMC WOUND SERVICES832531807SCGeneral Acute Care Hospital (282N00000X)
United
81241$75.021669480323 - KELL WEST REGIONAL HOSPITAL LLC752756307 - KELL WEST REGIONAL HOSPITAL, LLCTXGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81241 vs. Other Molecular Pathology Procedures Codes

The CPT 81241 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81241 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81235-CPTModerateEgfr (Epidermal Growth Factor Receptor) (Eg, Non-Small Cell Lung Cancer) Gene Analysis, Common Variants (Eg, Exon 19 Lrea Deletion, L858r, T790m, G719a, G719s, L861q)
81238-CPTModerateF9 (Coagulation Factor Ix) (Eg, Hemophilia B), Full Gene Sequence
81240-CPTLowF2 (Prothrombin Coagulation Factor Ii) (Eg Hereditary Hypercoagulability) Gene Analysis 20210g>A Variant
81241-CPTLowF5 (Coagulation Factor V)(Eg Hereditary Hypercoagulability) Gene Analysis Leiden Variant

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81241. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81241 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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