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CPT 81264 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Igk Rearrangeabn Clonal Pop, Igk Immunoglobulin Kappa Light Chain Locus Eg Leukemia And Lymphoma B Cell Gene Rearrangement Analysis Evaluation To Detect Abnormal Clonal Population S
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

None

XU - Unusual Non-Overlapping Service

XE - Separate encounter

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81264
Medicaid Fee ScheduleView Medicaid rates for 81264

National average reimbursement for CPT 81264 by major payers:

bcbs

$142.04

uhc

$114.37

aetna

$167.96

cigna

$271.95

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81264.

CPT 81264
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $380.01Published rate
  2. Christopher Raio

    St Joseph Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-3438973

    $204.63Published rate
  3. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1821081720Tax ID 59-3582520

    $151.05Published rate
  4. Christopher Raio

    St Francis Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-2050523

    $93.27Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $60.45Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81264 vs. Other Molecular Pathology Procedures Codes

The CPT 81264 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81264 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81263-CPTModerateIgh@ (Immunoglobulin Kappa Light Chain Locus) (Eg, Leukemia And Lymphoma, B-Cell), Gene Rearrangement Analysis, Evaluation To Detect Abnormal Clonal Population(S)
81264-CPTLowIgk Rearrangeabn Clonal Pop, Igk Immunoglobulin Kappa Light Chain Locus Eg Leukemia And Lymphoma B Cell Gene Rearrangement Analysis Evaluation To Detect Abnormal Clonal Population S
81265-CPTLowStr Markers Specimen Anal, Comparative Analysis Using Short Tandem Repeat Str Markers Patient And Comparative Specimen Eg Pre Transplant Recipient And Donor Germline Testing Post Transplant Non Hematopoietic Recipient Germline Eg Buccal Swab Or Other Germline Tissue Sample And Donor Testing Twin Zygosity Testing Or Maternal Cell Contamination Of Fetal Cells
81266-CPTModerateStr Markers Spec Anal Addl, Comparative Analysis Using Short Tandem Repeat Str Markers Each Additional Specimen Eg Additional Cord Blood Donor Additional Fetal Samples From Different Cultures Or Additional Zygosity In Multiple Birth Pregnancies List Separately In Addition To Code For Primary Procedure

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81264. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81264 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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