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CPT 81310 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Genetic Test For Leukemia, A Lab Analysis Of Genetic Material That Can Indicate Acute Myeloid Leukemia. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

59 - Distinct Procedural Service

26 - Professional component

Complexity LevelLow
Medicare Fee Schedule$246.52 national lab fee schedule rate (2026) · View Medicare rates for 81310
Medicaid Fee Schedule$217.435 median of the 8 states in the free preview · View Medicaid rates for 81310

National average reimbursement for CPT 81310 by major payers:

bcbs

$192.69

uhc

$151.24

aetna

$214.74

cigna

$376.94

Compare published rates across providers.

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CPT 81310
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $542.34Published rate
  2. Christopher Raio

    St Francis Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-2050523

    $325.41Published rate
  3. Christopher Raio

    St Joseph Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-3438973

    $248.25Published rate
  4. Michael Shuler

    Athens Orthopedic Clinic, PA

    GAOrthopaedic Hand Surgery PhysicianNPI 1497944565Tax ID 58-1076549

    $147.91Published rate
  5. Brittany Ptachick

    Hroa 401k Plan

    VAFamily Nurse PractitionerNPI 1053866707Tax ID 54-1958039

    $103.54Published rate

National sample. Rates vary by location, specialty, and contract.

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Payer Contract Negotiation

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CPT 81310 vs. Other Molecular Pathology Procedures Codes

The CPT 81310 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81310 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81310-CPTLowGenetic Test For Leukemia, A Lab Analysis Of Genetic Material That Can Indicate Acute Myeloid Leukemia. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81311-CPTModerateNras Gene Variants Exon 2 3, Nras Neuroblastoma Ras Viral V Ras Oncogene Homolog Eg Colorectal Carcinoma Gene Analysis Variants In Exon 2 Eg Codons 12 And 13 And Exon 3 Eg Codon 61
81312-CPTLowPabpn1 Gene Detc Abnor Allel, Pabpn1 Poly A Binding Protein Nuclear 1 Eg Oculopharyngeal Muscular Dystrophy Gene Analysis Evaluation To Detect Abnormal Eg Expanded Alleles
81322-CPTLowCowden Syndrome Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate Cowden Syndrome. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81310. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81310 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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