CPT 81312 Fee Schedule
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Molecular Pathology Procedures |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | None 90 - Reference Laboratory XU - Unusual Non-Overlapping Service |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 81312 |
| Medicaid Fee Schedule | View Medicaid rates for 81312 |
National average reimbursement for CPT 81312 by major payers:

$111.27

$83.99

$128.74

$209.39
CPT 81312 vs. Other Molecular Pathology Procedures Codes
The CPT 81312 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81312 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81305-CPT | Low | Myd88 Gene P Leu265pro Vrnt, Myd88 Myeloid Differentiation Primary Response 88 Eg Waldenstrom S Macroglobulinemia Lymphoplasmacytic Leukemia Gene Analysis P Leu265pro L265p Variant |
| 81310-CPT | Low | Genetic Test For Leukemia, A Lab Analysis Of Genetic Material That Can Indicate Acute Myeloid Leukemia. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints. |
| 81311-CPT | Moderate | Nras Gene Variants Exon 2 3, Nras Neuroblastoma Ras Viral V Ras Oncogene Homolog Eg Colorectal Carcinoma Gene Analysis Variants In Exon 2 Eg Codons 12 And 13 And Exon 3 Eg Codon 61 |
| 81312-CPT | Low | Pabpn1 Gene Detc Abnor Allel, Pabpn1 Poly A Binding Protein Nuclear 1 Eg Oculopharyngeal Muscular Dystrophy Gene Analysis Evaluation To Detect Abnormal Eg Expanded Alleles |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81312. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81312 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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