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CPT 81348 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Srsf2 Gene Common Variants, Srsf2 Serine And Arginine Rich Splicing Factor 2 Eg Myelodysplastic Syndrome Acute Myeloid Leukemia Gene Analysis Common Variants Eg P95h P95l
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

21 - Inpatient Hospital

22 - On Campus Outpatient Hospital

Common Modifiers

None

59 - Distinct Procedural Service

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81348
Medicaid Fee ScheduleView Medicaid rates for 81348

National average reimbursement for CPT 81348 by major payers:

bcbs

$159.31

uhc

$107.51

aetna

$161.42

cigna

$265.95

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81348.

CPT 81348
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $385.88Published rate
  2. Christopher Raio

    Samaritan Emergency Medical Services PC

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 20-8243412

    $231.53Published rate
  3. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $175.40Published rate
  4. Christopher Raio

    Good Samaritan Hosptial Medical Center

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-1888924

    $105.24Published rate
  5. Patrick Reidy

    Florida Gulf Coast Ear, Nose And Throat, LLC

    FLOtolaryngology PhysicianNPI 1194752840Tax ID 20-2399514

    $61.39Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81348 vs. Other Molecular Pathology Procedures Codes

The CPT 81348 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81348 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81347-CPTLowSf3b1 Gene Common Variants, Sf3b1 Splicing Factor 3b Subunit B1 Eg Myelodysplastic Syndrome Acute Myeloid Leukemia Gene Analysis Common Variants Eg A672t E622d L833f R625c R625l
81348-CPTLowSrsf2 Gene Common Variants, Srsf2 Serine And Arginine Rich Splicing Factor 2 Eg Myelodysplastic Syndrome Acute Myeloid Leukemia Gene Analysis Common Variants Eg P95h P95l
81349-CPTHighCytogenomic (Genome-Wide) Anal, Cytogenomic (Genome-Wide) Analysis For Constitutional Chromosomal Abnormalities Interrogation Of Genomic Regions For Copy Number And Loss-Of-Heterozygosity Variants Low-Pass Sequencing Analysis

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81348. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81348 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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