Data Platform
Sign InTry for Free

CPT 81422 Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Fetal Chromosomal Microdeletion(S) Genomic Sequence Analysis (Eg Digeorge Syndrome Cri-Du-Chat Syndrome) Circulating Cell-Free Fetal Dna In Maternal Blood
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

59 - Distinct Procedural Service

90 - Reference Laboratory

Complexity LevelModerate

National average reimbursement for CPT 81422 by major payers:

bcbs

$650.84

uhc

$477.08

aetna

$713.56

cigna

$1,109.22

Preview provider-level rates for...
For billing codeCPT 81422
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81422

United
81422$4165.351033464821 - JESSICA TENNEY943281660CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$1230.911073054722 - HELIO COSTA770465765CAClinical Molecular Genetics Physician (207SG0203X)
United
81422$4165.351972034841 - DAVID BLAIR943281657CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$948.801780818302 - NIKKI MADSON943281666CAGenetic Counselor (M.S.) (170300000X)
United
81422$4165.351831403211 - HIND AL SAIF943281666CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$797.001780818302 - NIKKI MADSON943281666CAGenetic Counselor (M.S.) (170300000X)
United
81422$3094.501275612749 - NICOLA LONGO954377219CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$3748.801033464821 - JESSICA TENNEY943281657CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$336.981316936990 - EL PASO COUNTY HOSPITAL DISTRICT, UNIVERSITY MEDICAL CENTER OF EL PASO746000756 - (TX) EL PASO COUNTY HOSPITAL DISTRICTTXGeneral Acute Care Hospital (282N00000X)
United
81422$336.261396014866 - KATHRYN SINGH271504911 - (CA) MEMORIALCARE MEDICAL FOUNDATIONCAGenetic Counselor (M.S.) (170300000X)
United
81422$1203.501952424079 - CATHERINE KARIMOV222095812 - UNIVERSITY PHYSICIAN ASSOCIATES OF NEW JERSEY INCCAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$797.001255548327 - JOSE CAMACHO943281657CAClinical Genetics (M.D.) Physician (207SG0201X)
United
81422$3516.531235165796 - WAYNE GRODY954377219CAMolecular Genetic Pathology (Pathology) Physician (207ZP0007X)
United
81422$3516.531902531288 - DAYNA RICHARDS954377219CAGenetic Counselor (M.S.) (170300000X)
United
81422$1161.341164541181 - MATTHEW DEARDORFF274470693CAClinical Genetics (M.D.) Physician (207SG0201X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

Want to see your competitors' rates?

Start your trial today to unlock complete access to provider rates and fee schedules in your area.

Here's what you can do with PayerPrice

Renegotiate your managed care contracts

Benchmark your current rates against market averages to identify opportunities for rate optimization.

Prospect for new business using fee schedules

Access every provider's negotiated rates for every billing code in your market to inform your prospecting strategies.

Integrate real-time payer data into your workflows

Automatically keep fee schedules up-to-date without adding yet another log-in to your insurance systems. Connect via API or SQL.

PayerPrice shows you the exact negotiated rates that insurers publish under federal transparency rules.
We display the raw data directly from insurers' files, giving you the same information they make public. Learn more about Price Transparency.

CPT 81422 vs. Other Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Codes

The CPT 81422 code is part of the Pathology and Laboratory Procedures services used for Genomic Sequencing Procedures and Other Molecular Multianalyte Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81422 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81420-CPTModerateFetal Chromosomal Aneuploidy (Eg, Trisomy 21, Monosomy X) Genomic Sequence Analysis Panel, Circulating Cell-Free Fetal Dna In Maternal Blood, Must Include Analysis Of Chromosomes 13, 18, And 21
81422-CPTModerateFetal Chromosomal Microdeletion(S) Genomic Sequence Analysis (Eg Digeorge Syndrome Cri-Du-Chat Syndrome) Circulating Cell-Free Fetal Dna In Maternal Blood
81441-CPTHighInherited Bone Marrow Failure Syndromes (Ibmfs) (Eg, Fanconi Anemia, Dyskeratosis Congenita, Diamond-Blackfan Anemia, Shwachman-Diamond Syndrome, Gata2 Deficiency Syndrome, Congenital Amegakaryocytic Thrombocytopenia) Sequence Analysis Panel, Must Include Sequencing Of At Least 30 Genes, Including Brca2, Brip1, Dkc1, Fanca, Fancb, Fancc, Fancd2, Fance, Fancf, Fancg, Fanci, Fancl, Gata1, Gata2, Mpl, Nhp2, Nop10, Palb2, Rad51c, Rpl11, Rpl35a, Rpl5, Rps10, Rps19, Rps24, Rps26, Rps7, Sbds, Tert, And Tinf2
81442-CPTHighNoonan Spectrum Disorders (Eg Noonan Syndrome Cardio-Facio-Cutaneous Syndrome Costello Syndrome Leopard Syndrome Noonan-Like Syndrome) Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 12 Genes Including Braf Cbl Hras Kras Map2k1 Map2k2 Nras Ptpn11 Raf1 Rit1 Shoc2 And Sos1

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81422. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81422 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

FREE SAMPLE MARKET COMPARISON

Let's review your payer contracts side-by-side with the market.

Bring your top codes (like CPT 81422) and we'll show you how you compare in 15 minutes or less.