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See a sample rate comparisonCPT 81507 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Fetal Aneuploidy Trisom Risk, Fetal Aneuploidy Trisomy 21 18 And 13 Dna Sequence Analysis Of Selected Regions Using Maternal Plasma Algorithm Reported As A Risk Score For Each Trisomy
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Multianalyte Assays with Algorithmic Analyses |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | QW - CLIA Waived Tests 90 - Reference Laboratory |
| Complexity Level | Moderate |
| Medicare Fee Schedule | $795.00 national lab fee schedule rate (2026) · View Medicare rates for 81507 |
| Medicaid Fee Schedule | $731.405 median of the 8 states in the free preview · View Medicaid rates for 81507 |
National average reimbursement for CPT 81507 by major payers:
$612.05
$487.27
$754.81
$1,154.55
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CPT 81507
5 of 25 sample ratesHigher to lower in this preview
Athena Angelopoulos
$4,362.64Published rateKevin Mcdonnell
City Of Hope Medical Foundation
$2,690.43Published rateSt. David'S Healthcare Partnership, L.P., LLP, St. David'S South Austin Medical Center
$795.00Published rateGrace Kavanaugh
Tennessee Oncology PLLC
$715.50Published rateConcordia Parish Hospital Service District Number One, Trinity Medical
Riverland Medical Center
$333.89Published rate
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See a sample payer proposalCPT 81507 vs. Other Multianalyte Assays with Algorithmic Analyses Codes
The CPT 81507 code is part of the Pathology and Laboratory Procedures services used for Multianalyte Assays with Algorithmic Analyses. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81507 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81490-CPT | Moderate | Autoimmune (Rheumatoid Arthrit, Autoimmune (Rheumatoid Arthritis) Analysis Of 12 Biomarkers Using Immunoassays Utilizing Serum Prognostic Algorithm Reported As A Disease Activity Score |
| 81493-CPT | Moderate | Coronary Artery Disease Mrna, Coronary Artery Disease Mrna Gene Expression Profiling By Real-Time Rt-Pcr Of 23 Genes Utilizing Whole Peripheral Blood Algorithm Reported As A Risk Score |
| 81506-CPT | Low | Endo Assay Seven Anal, Endocrinology Type 2 Diabetes Biochemical Assays Of Seven Analytes Glucose Hba1c Insulin Hs Crp Adiponectin Ferritin Interleukin 2 Receptor Alpha Utilizing Serum Or Plasma Algorithm Reporting A Risk Score |
| 81507-CPT | Moderate | Fetal Aneuploidy Trisom Risk, Fetal Aneuploidy Trisomy 21 18 And 13 Dna Sequence Analysis Of Selected Regions Using Maternal Plasma Algorithm Reported As A Risk Score For Each Trisomy |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81507. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81507 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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