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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Cytogenetic Studies |
| Common Place of Service | 81 - Independent Laboratory 21 - Inpatient Hospital |
| Common Modifiers | None 26 - Professional component 91 - Repeat Lab Test |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 88248 |
| Medicaid Fee Schedule | View Medicaid rates for 88248 |
National average reimbursement for CPT 88248 by major payers:

$172.11

$169.05

$185.01

$257.34
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Charleston Radiologists, P.A.
Baycare Home Care Inc
Mercy Medical Center
Hroa 401k Plan
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Rate Benchmarking
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See a sample payer proposalCPT 88248 vs. Other Cytogenetic Studies Codes
The CPT 88248 code is part of the Pathology and Laboratory Procedures services used for Cytogenetic Studies. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88248 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88241-CPT | Low | Cell Thawing, Cells That Have Been Frozen For Long-Term Storage Must Be Thawed Prior To Their Use Or Before Any Testing Can Be Done On Them. Each Cell Group Or Sample Is Thawed Separately. |
| 88245-CPT | Low | Chromosome Breakage Analysis, Chromosome Breakage Affects An Individuals Genetic Makeup. Breakage May Appear As A Weakness In The Chromosome Strand Or As Rearrangement Of Characteristics Rather Than Exact Copies In Each Strand. |
| 88248-CPT | Low | Chromosome Breakage Analysis, Chromosome Breakage Affects An Individuals Genetic Makeup. Breakage May Appear As A Weakness In The Chromosome Strand Or As Rearrangement Of Characteristics Rather Than Exact Copies In Each Strand. |
| 88249-CPT | Low | Chromosome Breakage Analysis, Chromosome Breakage Affects An Individuals Genetic Makeup. Breakage May Appear As A Weakness In The Chromosome Strand Or As Rearrangement Of Characteristics Rather Than Exact Copies In Each Strand. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88248. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88248 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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