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See a sample rate comparisonCPT 88341 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Immunohistochemistry Or Immuno, Immunohistochemistry Or Immunocytochemistry Per Specimen Each Additional Single Antibody Stain Procedure (List Separately In Addition To Code For Primary Procedure)
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 22 - On Campus Outpatient Hospital 81 - Independent Laboratory |
| Common Modifiers | 26 - Professional component 59 - Distinct Procedural Service |
| Complexity Level | Low |
| Medicare Fee Schedule | $94.19 national non-facility rate (2026) · View Medicare rates for 88341 |
| Medicaid Fee Schedule | $78.155 median of the 8 states in the free preview · View Medicaid rates for 88341 |
National average reimbursement for CPT 88341 by major payers:
$98.32
$71.33
$96.19
$100.09
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CPT 88341
5 of 25 sample ratesHigher to lower in this preview
Farid Moussavi-Harami
Association Of University Physicians
$185.63Published rateJalal Andre
Association Of University Physicians
$126.40Published ratePeter Legnani
New York Gastroenterology Associates, LLP
$67.68Published rateMaureen Daye
Lawrence Medical Associates PC
$49.90Published rateYitzhak Twersky
St Johns Medical Services PC
$14.63Published rate
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See a sample payer proposalCPT 88341 vs. Other Surgical Pathology Procedures Codes
The CPT 88341 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88341 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88341-CPT | Low | Immunohistochemistry Or Immuno, Immunohistochemistry Or Immunocytochemistry Per Specimen Each Additional Single Antibody Stain Procedure (List Separately In Addition To Code For Primary Procedure) |
| 88342-CPT | Low | Immunohistochemistry Or Immuno, Immunohistochemistry Or Immunocytochemistry Each Separately Identifiable Antibody Per Block Cytologic Preparation Or Hematologic Smear First Separately Identifiable Antibody Per Slide |
| 88344-CPT | Low | Typing Of Diseased Cells, Microscopic Examination Of A Tissue Sample. It Is Usually Used To Identify The Type Of Cancer Present (Or Predict The Outcome Of A Cancer). |
| 88350-CPT | Low | Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88341. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88341 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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