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See a sample rate comparisonCPT 88350 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 22 - On Campus Outpatient Hospital 81 - Independent Laboratory |
| Common Modifiers | 26 - Professional component 59 - Distinct Procedural Service |
| Complexity Level | Low |
| Medicare Fee Schedule | $106.88 national non-facility rate (2026) · View Medicare rates for 88350 |
| Medicaid Fee Schedule | $90.78 median of the 8 states in the free preview · View Medicaid rates for 88350 |
National average reimbursement for CPT 88350 by major payers:
$117.25
$72.56
$107.12
$116.67
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CPT 88350
5 of 25 sample ratesHigher to lower in this preview
Sabrina Martin
$498.95Published rateMichael Rains
Beacon Dermatology LLC
$59.34Published rateKatherine Kenneweg
$40.59Published rateJessica Connett
Dermatology Associates PA
$27.18Published rateJaime Vanourny
Piedmont Plastic Surgery & Dermatology, P.A.
$15.93Published rate
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See a sample payer proposalCPT 88350 vs. Other Surgical Pathology Procedures Codes
The CPT 88350 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88350 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88341-CPT | Low | Immunohistochemistry Or Immuno, Immunohistochemistry Or Immunocytochemistry Per Specimen Each Additional Single Antibody Stain Procedure (List Separately In Addition To Code For Primary Procedure) |
| 88346-CPT | Low | Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis. |
| 88348-CPT | Moderate | Microscopic Exam Of Sample, Microscopic Exam Of A Tissue Sample. The Examination Aids Diagnosis Of Cancerous Tumors. |
| 88350-CPT | Low | Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88350. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88350 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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