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CPT 80361 Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Definitive Drug Testing; Opiates, 1 Or More
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 80361

National average reimbursement for CPT 80361 by major payers:

bcbs

$22.25

uhc

$16.35

aetna

$3.15

cigna

$60.10

Preview provider-level rates for...
For billing codeCPT 80361
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 80361

United
80361$14.511679578439 - MOTHER FRANCES HOSPITAL REGIONAL HEALTH CARE CENTER, CHRISTUS MOTHER FRANCES HOSPITAL TYLER750818167 - (TX) MOTHER FRANCES HOSPITAL REGIONAL HEALTH CARE CENTERTXGeneral Acute Care Hospital (282N00000X)
United
80361$20.101851768337 - KELLY RIDGES362925195 - ALLERGY & ASTHMA OF DUPAGE, S.C.ILFamily Nurse Practitioner (363LF0000X)
United
80361$10.151942294939 - ST JOSEPH REGIONAL HEALTH CENTER, ST JOSEPH AMBULATORY SURGERY741282696 - ST JOSEPH REGIONAL HEALTH CENTERTXGeneral Acute Care Hospital (282N00000X)
United
80361$31.471689676835 - NATCHITOCHES PARISH HOSPITAL SERVICE DISTRICT, NATCHITOCHES REGIONAL MEDICAL CENTER726013916 - (LA) NATCHITOCHES REGIONAL MEDICAL CENTERLAGeneral Acute Care Hospital (282N00000X)
United
80361$10.361407191984 - BSA HOSPITAL LLC900914340TXGeneral Acute Care Hospital (282N00000X)
United
80361$10.391013964113 - EYECARE ASSOCIATES PC930590581 - EYECARE ASSOCIATES PCOROphthalmology Physician (207W00000X)
United
80361$12.571366400376 - SUNRISE HOME HEALTH CARE INC.650307774 - (FL) SUNRISE HOME HEALTH CARE INCFLHome Health Agency (251E00000X)
United
80361$10.151679845531 - DANA HEMSTREET451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALFamily Nurse Practitioner (363LF0000X)
United
80361$34.871255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
80361$17.451033117007 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80361$10.151306540380 - KARLIE RYAN451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALFamily Nurse Practitioner (363LF0000X)
United
80361$14.301851400485 - GEORGE HEMSTREET451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALInterventional Cardiology Physician (207RI0011X)
United
80361$17.611255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
80361$14.511295736734 - CHRISTUS HEALTH ARK-LA-TEX, CHRISTUS ST. MICHAEL HEALTH SYSTEM752616977 - CHRISTUS TRINITY CLINICTXGeneral Acute Care Hospital (282N00000X)
United
80361$10.151689650921 - EASTLAND MEMORIAL HOSPITAL DISTRICT, EASTLAND MEMORIAL HOSPITAL752313255TXGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 80361 vs. Other Therapeutic Drug Assays Codes

The CPT 80361 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80361 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80346-CPTLowDefinitive Drug Testing; Benzodiazepines; 1-12
80355-CPTLowDefinitive Drug Testing; Gabapentin, Non-Blood
80359-CPTLowDefinitive Drug Testing; Methylenedoxyamphetamines (Mda, Mdea, Mdma)
80361-CPTLowDefinitive Drug Testing; Opiates, 1 Or More

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80361. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80361 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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