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CPT 81256 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Iron Condition Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate A Problem With Too Much Iron (Hemochromatosis). Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81256
Medicaid Fee ScheduleView Medicaid rates for 81256

National average reimbursement for CPT 81256 by major payers:

bcbs

$56.67

uhc

$46.81

aetna

$72.72

cigna

$119.76

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81256.

CPT 81256
5 of 25 sample ratesHigher to lower in this preview
  1. Dallas Vamc

    TXGeneral Acute Care HospitalNPI 1932729803Tax ID 75-6108647

    $89.16Published rate
  2. Canyon Atlantic

    TXGeneral Acute Care HospitalNPI 1871137513Tax ID 84-3385649

    $65.36Published rate
  3. Jackson Parish Hospital, Jackson Parish Hospital

    LACritical Access HospitalNPI 1093793408Tax ID 72-0549907

    $65.36Published rate
  4. Tenet Hospitals Limited, The Hospitals Of Providence Transmountain Campus

    TXGeneral Acute Care HospitalNPI 1538522412Tax ID 95-4537720

    $65.36Published rate
  5. Val Verde Hospital Corporation, Val Verde Regional Medical Center

    Val Verde Hospital Corporation

    TXGeneral Acute Care HospitalNPI 1104830900Tax ID 74-2941598

    $27.45Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81256 vs. Other Molecular Pathology Procedures Codes

The CPT 81256 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81256 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81255-CPTLowTay-Sachs Disease Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate Tay-Sachs Disease. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81256-CPTLowIron Condition Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate A Problem With Too Much Iron (Hemochromatosis). Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81257-CPTLowHba/Hba2 (Alpha Globin 1 And Alpha Globin 2) (Eg Alpha Thalassemia Hb Bart Hydrops Fetalis Syn- Drome Hbh Disease) Gene Analysis Common Deletions Or Variant (Eg Southeast Asian Thai Filipino Mediterranean Alpha3.7 Alpha4.2 Alpha20.5 And Constant Spring) (Desc Revised 1/1/2018)
81258-CPTModerateHba1hba2 (Alpha Globin 1 And, Hba1hba2 (Alpha Globin 1 And Alpha Globin 2) (Egalpha Thalassemia Hb Bart Hydrops Fetalis Syndro Me Hbh Disease) Gene Analysis Known Familial Variant (Eg Exon 12) Hpa-9ab (V837m)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81256. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81256 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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