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CPT 81552 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Onc Uveal Mlnma Mrna 15 Gene, Oncology Uveal Melanoma Mrna Gene Expression Profiling By Real Time Rt Pcr Of 15 Genes 12 Content And 3 Housekeeping Utilizing Fine Needle Aspirate Or Formalin Fixed Paraffin Embedded Tissue Algorithm Reported As Risk Of Metastasis
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Multianalyte Assays with Algorithmic Analyses

Common Place of Service

81 - Independent Laboratory

Complexity LevelHigh
Medicare Fee Schedule$7,776.00 national lab fee schedule rate (2026) · View Medicare rates for 81552
Medicaid Fee Schedule$7,776.00 median of the 8 states in the free preview · View Medicaid rates for 81552

National average reimbursement for CPT 81552 by major payers:

bcbs

$7,096.86

uhc

$4,748.53

aetna

$6,160.23

cigna

$11,264.06

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81552.

CPT 81552
5 of 25 sample ratesHigher to lower in this preview
  1. Matthew Lilley

    Bend Memorial Clinic, PC

    OROrthopaedic Surgery PhysicianNPI 1003166612Tax ID 68-0637976

    $11,664.00Published rate
  2. Christopher Raio

    Good Samaritan Hosptial Medical Center

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-1888924

    $9,237.89Published rate
  3. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1720087513Tax ID 59-3582520

    $5,734.33Published rate
  4. Bradley Weisner

    Urology Specialists Of The Carolinas, PLLC

    NCUrology PhysicianNPI 1619910627Tax ID 56-2107759

    $3,888.00Published rate
  5. Sunrise Home Health Care Inc.

    Sunrise Home Health Care Inc

    FLHome Health AgencyNPI 1366400376Tax ID 65-0307774

    $3,110.39Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81552 vs. Other Multianalyte Assays with Algorithmic Analyses Codes

The CPT 81552 code is part of the Pathology and Laboratory Procedures services used for Multianalyte Assays with Algorithmic Analyses. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81552 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81541-CPTHighOncology (Prostate) Mrna Gene, Oncology (Prostate) Mrna Gene Expression Profiling By Real-Time Rt-Pcr Of 46 Genes (31 Content And 15 Housekeeping) Utilizing Formalin-Fixed Paraffin-Embedded Tissue Algorithm Reported As A Disease-Specific Mortality Risk Score Hpa-9ab (V837m)
81542-CPTHighOnc Prostate Mrna 22 Cnt Gen, Oncology Prostate Mrna Microarray Gene Expression Profiling Of 22 Content Genes Utilizing Formalin Fixed Paraffin Embedded Tissue Algorithm Reported As Metastasis Risk Score
81546-CPTHighOnc Thyr Mrna 10 196 Gen Alg, Oncology Thyroid Mrna Gene Expression Analysis Of 10 196 Genes Utilizing Fine Needle Aspirate Algorithm Reported As A Categorical Result Eg Benign Or Suspicious
81552-CPTHighOnc Uveal Mlnma Mrna 15 Gene, Oncology Uveal Melanoma Mrna Gene Expression Profiling By Real Time Rt Pcr Of 15 Genes 12 Content And 3 Housekeeping Utilizing Fine Needle Aspirate Or Formalin Fixed Paraffin Embedded Tissue Algorithm Reported As Risk Of Metastasis

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81552. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81552 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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