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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 22 - On Campus Outpatient Hospital 21 - Inpatient Hospital |
| Common Modifiers | 26 - Professional component TC - Technical component |
| Complexity Level | Moderate |
| Medicare Fee Schedule | $477.97 national non-facility rate (2026) · View Medicare rates for 88348 |
| Medicaid Fee Schedule | $407.53 median of the 8 states in the free preview · View Medicaid rates for 88348 |
National average reimbursement for CPT 88348 by major payers:

$524.48

$381.38

$531.60

$501.49
Choose a payer to see a sample of rates for CPT 88348.
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
Christopher Raio
Mercy Medical Center
Christopher Raio
St Francis Hospital
Christopher Raio
Mercy Medical Center
All Ways Homecare Inc
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Rate Benchmarking
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See a sample rate comparisonPayer Contract Negotiation
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See a sample payer proposalCPT 88348 vs. Other Surgical Pathology Procedures Codes
The CPT 88348 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88348 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88341-CPT | Low | Immunohistochemistry Or Immuno, Immunohistochemistry Or Immunocytochemistry Per Specimen Each Additional Single Antibody Stain Procedure (List Separately In Addition To Code For Primary Procedure) |
| 88346-CPT | Low | Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis. |
| 88348-CPT | Moderate | Microscopic Exam Of Sample, Microscopic Exam Of A Tissue Sample. The Examination Aids Diagnosis Of Cancerous Tumors. |
| 88350-CPT | Low | Immune Study Tissue Sample, For This Study Antibodies From A Tissue Sample Are Treated With Fluorescent Dye And Then Examined Under A Microscope. Intensity Pattern And Distribution Of The Antibodies Aid Diagnosis. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88348. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88348 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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